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Moreover, the thioether sulfur on the straight chain was more susceptible to oxygen transfer with PMS than that on the thiazole ring of HRAs. Toxicity evaluation indicated the ecotoxicity of HRAs could be remarkably reduced after PMS oxidation. Hence, this work provides a promising strategy to rapidly remove HRAs and significantly reduce their toxicity in water treatment. Blastocystis is a unicellular protozoan and one of the most common parasites found in humans and many animals' intestinal tract. The present study aimed to compare the