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Madagascar and the Mascarene Islands of Mauritius and Rodrigues underwent catastrophic ecological and landscape transformations, which virtually eliminated their entire endemic vertebrate megafauna during the past millennium. These ecosystem changes have been alternately attributed to either human activities, climate change, or both, but parsing their relative importance, particularly in the case of Madagascar, has proven difficult. Here, we present a multimillennial (approximately the past 8000 years) reconstruction of the southwest Ind

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s and balloon lengths. Compared to conventional HPB angioplasty, DCB treatment achieved superior primary patency defined using PSVR measured at 6 months and superior intervention-free survival of both the target lesion and the target shunt at 12 months without evidence of greater adverse events. Funded by ZhuHai Cardionovum Medical Device Co., Ltd. Registered at ClinicalTrials.gov with study number NCT02962141. Registered at ClinicalTrials.gov with study number NCT02962141. To identify differences in socioeconomic factors (SES) and subc