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id receptor antagonist dosing regimens for patients undergoing either short- or long-segment spinal arthrodesis procedures. Methylnaltrexone did not accelerate gastrointestinal recovery and did not affect opioid consumption or pain scores following short-segment spinal surgery as compared to placebo. Additional studies will be needed to identify effective opioid receptor antagonist dosing regimens for patients undergoing either short- or long-segment spinal arthrodesis procedures. Cervical total disc arthroplasty (TDA) is an alternative