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This study aimed to investigate the role of endothelial Piezo1 in mediating ventilator-induced lung injury secondary to acute respiratory distress syndrome (ARDS). Rats and lung endothelial cells (ECs) were transfected with Piezo1 shRNA (shPiezo1) and Piezo1 siRNA, respectively, to knock down Piezo1. Intratracheal instillation or incubation with lipopolysaccharide (LPS) was used to establish an ARDS model, and high tidal volume (HVT) ventilation or 20% cyclic stretch (CS) was administered to simulate a two-hit injury. Lung injury, alterati

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NYCHA and EV Micro-Mobility The EV micro-mobility system is an economical method of filling gaps in the first and last mile and complements public transportation. NYCHA recognizes that e-bikes and escooters are vital to low-income residents and offer the opportunity to exercise, particularly when shared. They also pose a unique set problems. They must be monitored, tracked and controlled. Accessibility Electric micro-mobility has become a rapidly growing segment of the transportation sector. It offers servic