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If there is severe VOD diagnosed, then Defibrotide could be an option for treatment.Orchestra musicians are at high risk of neuro-mechanical disorders due to the intense stresses their body withstand, leading to pain and injury. This review presents a comprehensive account of the works on the circumstances and types of playing related mobility disorders of upper strings players, as well as on the relevant neuro-mechanical factors and perspectives to those disorders. The following aspects are considered asymmetry and imbalance in the mus

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