https://www.selleckchem.com/pr....oducts/BafilomycinA1
Fatty acid biosynthesis, the expression of the metabolism-related genes ACC1, FASN, SCD1, and DGAT1, and the levels of inflammatory factors were higher in HFD mice than in NC mice and decreased after SG. NAD+concentrations were 54.9±13.4μmol/mg in NC-Sham mice, 37.6±8.1μmol/mg in HFD-Sham mice, and 79.9±13.0μmol/mg in HFD-SG mice (p0.05). NRK1 and SIRT1 expression increased dramatically after SG at both the RNA and protein levels. SG significantly alleviated NAFLD in HFD-induced obese mice with increasing the hepatic NAD+level
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