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1% (n = 2631) were found to have mild to severe depression, and 50.5% (n = 358 were affected by mild to severe anxiety. After adjusting for confounding factors, in women, the third (OR 1.41, 95% CI 1.06-1.88, p-values less then 0.05) and fourth quartiles (OR 1.37, 95% CI 1.03-1.83, p-values less then 0.05) of DII score were associated with increased risk of a high depression score compared to the first quartile of DII score. Conclusion There was a significant association between DII score and severe depression among women but not men in this Iranian popul