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Congenital cataracts is the most common cause of childhood visual impairment and blindness worldwide. It is reported that about one quarter of congenital cataracts caused by genetic defects. Various gene mutations have been identified in hereditary cataracts so far. The purpose of the present study was to investigate the relationship between gap junction protein alpha 8 ( ) gene mutation and congenital cataract. A pedigree with autosomal dominant congenital cataract was investigated and the peripheral venous blood was extra

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