https://www.selleckchem.com/pr....oducts/cid755673.htm
During mitotic chromosome segregation, the protease separase severs cohesin between sister chromatids. A probe for separase activity has shown that separase undergoes abrupt activation shortly before anaphase onset, after being suppressed throughout metaphase; however, the relevance of this control remains unclear. Here, we report that separase activates precociously, with respect to anaphase onset, during prolonged metaphase in multiple types of cancer cell lines. The artificial extension of metaphase in chromosomally stable diploid

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ADHD Assessment - What You Need to Know The NHS ADHD assessment services struggle to keep up with the high demand. This has resulted in long waiting lists and substandard assessment reports. A good assessment will be comprehensive and take at least two hours. The test will contain questions that have open-ended answers as well as actual examples. It will also cover issues with employment and education. It will cover mental health conditions that are comorbi