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0% and 2.0% ELE supplementation compared to the control. Larvae fed the diet with 1.0% ELE had a significantly higher activities of lysozyme, total nitric oxide synthase and nitric oxide content than the control. Moreover, transcriptional levels of cox-2, il-1β and il-6 were remarkably down-regulated by supplementation of 0.5-1.0% ELE. This study demonstrated that the supplementation of 1.0% ELE in diet could increase the growth performance of large yellow croaker larvae probably by promoting expression of feeding-related ge