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The heterogeneity of triple-negative breast cancer (TNBC) confers variable response to chemotherapy that results in poor outcome and relapse. Due to lack of targeted therapy, there is a need to provide molecular classification of TNBC and identify probable therapeutic targets. We classified TNBC into surrogate molecular subtypes by immunohistochemistry and evaluated hotspot mutations (N = 8 in PIK3CA (exon 4, 9, and 2 and AKT1 (exon 2) in TNBC subtypes by Sanger sequencing. TNBCs were classified into Basal-like 1(BL1) (n = 20, 25%),

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What is Cervical Cancer cells? Cervical cancer cells occurs in the cells of the cervix-- the reduced part of the womb that attaches to the vaginal canal. It is primarily caused by persistent infection with specific kinds of human papillomavirus (HPV). Cervical cancer is among one of the most avoidable kinds of cancer because of the availability of screening tests and injections. Kinds Of Cervical Cancer Cells - Squamous Cell Carcinoma: This kind starts in the slim, flat cells lining the external part of the cervix, which forecasts right into the vag