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What is Pragmatics? A person who understands the pragmatics of language can politely decline a request, read between lines or negotiate the rules of turn-taking in conversation. Pragmatics considers cultural, social, and situational factors into consideration when using language. Consider this The news report states that a stolen painting was discovered "by the trunk of a tree." This is an example of confusion that our understanding of pragmatics can help us disambiguate and facilitate everyday commun

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This study identified impairment of the ER/mitochondria compartment without SR dysfunction as a novel disease mechanism underlying PLN p.Arg14del cardiomyopathy. The pathology was improved by Ca2+ -scavenging, suggesting impaired local Ca2+ cycling as an important disease culprit. There is no proven primary preventive strategy for doxorubicin-induced subclinical cardiotoxicity (DISC), especially among patients without a cardiovascular (CV) risk. We investigated the primary preventive effect on DISC of the concomitant use of angiotensin