https://www.selleckchem.com/pr....oducts/Vorinostat-sa
Tumour-associated macrophages (TAMs) inhibit the killing effect of T lymphocytes on tumour cells through the immunocheckpoint programmed death ligand-1 (PD-L1)/programmed death-1 (PD-1) axis. TAMs-targeted therapy is a promising approach that could be used to reverse the immunosuppressive tumour microenvironment. Here, we further report CMPB90-1, a novel natural polysaccharide from Cordyceps militaris, could function as an anti-tumour modulator that resets TAMs from a tumour-promoting M2 phenotype to a tumour-killing M1 phenotyp

https://www.selleckchem.com/pr....oducts/nvp-bgt226.ht
RESULTS In the ex vivo simulation, 20 mock stones mimicking varied fragmentation conditions were tested in the training model. The mean completion time of the basketing task without versus with digital stone measurement was 16.5 seconds (range 10.2-33.7) versus 38.9 seconds (range 27.2-60.. Mean additional time required to measure stones was 22.3 seconds (range 8.4-42.7). In the in vivo workflow trial, 9 patients undergoing ureteroscopy were enrolled. A median of 5 fragments (range 3-1 were measured in each patient. Mean completi