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Adherence at baseline was a significant predictor of adherence post-intervention in the antidiabetic (OR = 6.5;P 0.0001) and antihypertensive (OR = 4.1; P = 0.0001 β = 0.09; P = 0.008) users. Physician specialty (OR = 3.902; P = 0.01 β = 0.09; P = 0.015) among antidiabetic users and age 70 years (OR = 2.148; P = 0.025) among antihypertensive users were predictors of adherence. The intervention targeting statin did not significantly improve antihypertensive/antidiabetic adherence. Targeted interventions tailored to

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Better statistical metrics characterize the models developed on larger populations (Chicago and Bordeaux models). However, no model has a valid benefit for threshold probability greater than 0.30. The Net benefit of the most performing model (Bordeaux model) at the threshold probability of 0.11 is 23 of 1000 patients, burdened by 333 false positive cases. One of 1000 is the Net benefit at the threshold probability of 0.3. The use of PAL scores based on preoperative predictive factors cannot be currently used in a clinical setting becau