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C (OR = 2.54; 95%CI 1.44-4.56; = 0.001). A similar result was observed in the comparison of the TT CC genotype between the control group and cirrhosis group (OR = 2.88; 95%CI 1.44-5.77; = 0.001) but not for HCC patients. In the dominant T allele model, the CT + TT genotypes were associated with an increased risk for progression to cirrhosis (OR = 2.60; 95%CI 1.63-4.19; 0.001) and HCC (OR = 2.45; 95%CI 1.42-4.31; = 0.001). These findings suggest that the T allele of rs12979860 polymorphism is associated with the development of cirrhosis and HCC

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