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The efficient delivery of hUCMSC-exos in PF-127 gel and improved exosome ability could promote diabetic wound healing. Thus, this biomaterial-based exosome therapy may represent a new therapeutic approach for cutaneous regeneration of chronic wounds. The efficient delivery of hUCMSC-exos in PF-127 gel and improved exosome ability could promote diabetic wound healing. Thus, this biomaterial-based exosome therapy may represent a new therapeutic approach for cutaneous regeneration of chronic wounds.Supramolecular vesicles are the most popular smart nano-drug d

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The analytical measuring range of the method for all steroids was 2.5, 5, or 10ng/ml to 250ng/ml in DBS, r ≥0.995. The LLOQ, intra-day and inter-day precision were 0.11-1.8ng/ml, 1.2-6.4ng/ml, 1.8-11.5%, and 5.3-13.8%, respectively. Our LC-MS/MS assay simultaneously detects 7 steroids for the diagnosis of CAH and can be readily implemented in clinical laboratories to provide superior analytical performance over traditional immunoassays. Our LC-MS/MS assay simultaneously detects 7 steroids for the diagnosis of CAH and can be readily i