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The detection of Δ152p53 isoform mRNA in serum is indicative of tumorigenesis. Furthermore, we showed a tissue-specific p53-dependent deregulation of the p63 and p73 isoforms in these tumours. This study highlights important species-specific differences in the transcriptional regulation of TP53. Considering the similarities of TP53 regulation between pig and human, these observations provide useful pointers for further investigation into isoform function including the novel circTP53 in both the pig model and human patients.Use of non-s

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How to Combine a Media Wall and an Electric Fire Media walls are a recent trend in home interiors. They are bespoke wall panels that include integrated storage like shelves and drawers or cabinets. They can also incorporate appliances like an electric fireplace. You can add a unique dimension to your media wall by installing the Gazco eStudio 105R wall-mounted media electric fire. Th