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tes. In this analysis, myopericarditis was most commonly reported after smallpox vaccine, and less commonly after other vaccines. Pakistan introduced Ten-valent pneumococcal-conjugate-vaccine PCV10 in 2012 as a 3+0 schedule without catch-up. Children 2years old in Matiari, Sindh provided nasopharyngeal swabs between 2014 and 2018, which were cultured for pneumococcus and serotyped through multiplex PCR at the Aga Khan University Hospital. Carriage rates over time for Vaccine-Type (VT) and Non-VT (NVT) serotypes were used to estimate di