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Cell surface proteins are known to assemble into nano- and microscale domains in order to govern biological processes, including cell adhesion, endocytosis, and immune responses. The small size and ephemerality of these structures have made their direct observation and functional analysis challenging. In this Perspective, I discuss recent progress made in applying nanotechniques to study protein clustering, emphasizing the use of state-of-the-art single-molecule atomic force microscopy, as reported by Strasser et al. in this issue of ACS Nano.Effect

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What's more, the reactive oxygen species obtained from combined SDT/CDT could efficiently trigger immunogenic cell death through a synergistic therapy based on the elicitation of antitumor immunity with the aid of an immune checkpoint blockade for the sake of suppressing primary and distant tumors as well as lung metastasis. Taken together, this paradigm delivers useful insights for developing in-coming nanocomposites based on cobalt ferrite for cancer theranostics.Targeted delivery of molecular cargos to specific organelles is of param