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The reproducibility of this BODIPY-ChE assay is excellent as the intra-assay coefficients of variation (CVs) were less then 10% (30 replicates on the same day) and the interassay CVs were less then 14% (10 experiments performed on different days, with 3 replicates each). The fluorescent method therefore represents a reproducible, safe and useful tool to evaluate ChE as an emerging cardiovascular risk factor.Macrophage foam cell formation plays a crucial role in the initiation and progression of atherosclerosis. Macrophages uptake nativ