https://www.selleckchem.com/pr....oducts/ch7233163.htm
'Pioneer' transcription factors are required for stem-cell pluripotency, cell differentiation and cell reprogramming1,2. Pioneer factors can bind nucleosomal DNA to enable gene expression from regions of the genome with closed chromatin. SOX2 is a prominent pioneer factor that is essential for pluripotency and self-renewal of embryonic stem cells3. Here we report cryo-electron microscopy structures of the DNA-binding domains of SOX2 and its close homologue SOX11 bound to nucleosomes. The structures show that SOX factors can bind and l

https://mccarty-mccullough-2.h....ubstack.net/why-nobo
https://postheaven.net/liquorb....anjo92/the-reasons-c
Remote Key Fob Repair Modern vehicles are equipped with remote controls that can be used to lock, unlock, and start the vehicle. As with any high-tech piece equipment, there are issues. Usually these are very simple to fix. You can reset it by following the steps in your owner’s manual. Check the Battery The remote control is powered by the battery in the key fob. It's a tiny and affordable part t