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Further, while the mRNA expression of neuropeptide, Tac1, precursor of Substance P, did not change at the transcriptional level, TAC1 protein expression increased in 24-month-old DRGs. Additionally, elevated expression of NFκB subunits, Nfkb1 and Rela, but not inflammatory mediators, Tnf, Il6, Il1b, or Cox2, in the DRGs suggest peripheral nerves are responding to inflammation, but do not increase the expression of inflammatory mediators at the transcriptional level. These results identify a progressive, age-related shift in the molecu

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A Double Mattress UK Is Ideal For Couples The most sought-after UK bed size is the double mattress. The double mattress is perfect for couples and suits many homes. The UK offers various sizes of beds including single, small double, double, king, and super king. The king and super king size beds are perfect for those who want plenty of space. Comfort A double mattress uk is perfect for couples who want to share a bed that allows them to relax and stretch out. It's also the