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The Most Comfortable Sectional Couch A sectional couch is an event space for household movie nights, cozy cuddles and reading sessions. These comfy sofas feature a combination of foam with fiber fill, luxurious upholstery and lots of modification choices. Some models consist of special functions like reclining seats and built-in USB ports. To discover the most comfortable, consider who will use the sofa and how often. Comfortable Seating A comfortable sectional so

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BAG3, a multifunctional HSP70 co-chaperone and anti-apoptotic protein that interacts with the ATPase domain of HSP70 through its C-terminal BAG domain plays a key physiological role in cellular proteostasis. The HSP70/BAG3 complex determines the levels of a large number of selective client proteins by regulating their turnover via the two major protein degradation pathways, i.e. proteasomal degradation and macroautophagy. On the one hand, BAG3 competes with BAG1 for binding to HSP70, thereby preventing the proteasomal degradation o