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Selecting a Comfortable Sleeper Sofa There are numerous factors to consider when selecting a comfortable sleeper sofa. These include the mattress type, frame building and construction and cushion feel. Quality frames made from kiln-dried wood are essential, as they are stronger than standard couch frames. In addition, the mechanism that converts the sofa into a bed is also crucial. 1. Comfortable Seating A sleeper sofa can double as a couch throughout the day and a bed at night, ma

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Amyotrophic Lateral Sclerosis is a progressive, incurable amyloid aggregating neurodegenerative disease involving the motor neurons. Identifying potential biomarkers and therapeutic targets can assist in the better management of the disease. We used an integrative approach encompassing analysis of transcriptomic datasets of human and mice from the GEO database. Our analysis of ALS patient datasets showed deregulation in Non-alcoholic fatty acid liver disease and oxidative phosphorylation. Transgenic mice datasets of SOD1, FUS and TDP-