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https://www.selleckchem.com/pr....oducts/3-methyladeni
036). As response to drug-related negative cues, TUD subjects showed no reduced activation of the aversive brain network. Within the TUD group, a significant negative association was found between response of the aversive brain system to drug-related negative cues (within-subjects effect P-values ≤ 0.021) and the number of cigarettes smoked per day (right insula r = -0.386, p = 0.024; left insula r = -0.351, p = 0.042; right ACC r = -0.359, p = 0.037). Moderate smokers with tobacco use disorder appear to have altered brain rewar