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001), the extract of significantly reduced ROS and cell apoptosis at concentrations ranging from 6.25 to 25 μg/mL (p0.01 and p0.001 respectively). Also, the extract significantly reduced MDA level in comparison with 6-OHDA (p0.001). The GSH level and SOD activity were increased by the extract. Findings of the current study showed that exerts it effect through inhibiting oxidative stress parameters and it can be considered a promising candidate to be used in combination with the conventional medications

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01-5.0 μM with the relative standard deviation of 3.49% (n = 5). The detection limit and quantification limit of the probe were determined to be 3.8 and 12 nM, respectively. The remarkable sensitivity and high selectivity of the method approved the sensor applicability in measurement of sarcosine content in urine samples.The low-cost e-fabrication of specialized multianalyte biosensors within the point-of-care (POC) settings in a few minutes remains a great challenge. Unlike prefabricated biosensors, 3D printing seems to be able to meet