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Strikingly, these mutations also influence the gut microbiome in mice. This review defines the alterations in gut physiology and microbiota in mouse types of autism with customized synapse purpose. The explanation for different areas of the gastrointestinal system having variable susceptibility to dysfunction is also discussed. To dissect fundamental biological mechanisms involving gut-brain axis disorder in preclinical models, a variety of multidisciplinary approaches are expected. This study will offe

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