Unlocking Gene Function: A Practical Guide to Functional Screening with CRISPR Libraries
In the era of genome editing, CRISPR-based functional screening has emerged as a powerful strategy for understanding gene function on a genome-wide scale. By leveraging large-scale CRISPR libraries, researchers can perform unbiased, high-throughput investigations that pinpoint genes associated with diverse cellular phenotypes—from drug resistance to immune evasion.
This article provides a clear, practical overview of how to design, build, and execute a functional screening platform using CRISPR libraries. We’ll walk through the foundational concepts, typical screening setups, selection strategies, and real-world applications.
Read more: https://www.ubigene.us/applica....tion/crispr-screenin
