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ADHD Medication - Ritalin Ritalin, a chemical called methylphenidate is effective in managing ADHD symptoms in adults. It can make people feel "up," alert, awake, and full of a an euphoria. ADHD medication works by altering dopamine and norepinephrine which are two brain chemicals. Most ADHD drugs are stimulants, such as Ritalin, Concerta, Focalin and Vyvanse. There are also nonstimulant medications. Methylphenidate Methylphenidate is a central nerve system stimulant that has been the mo