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The presence of autoantibodies was significantly related to age (P = 0.001), total number of transfused units (P = 0.00 and splenectomy (P = 0.00. The high prevalence of alloimmunization in the study population disclosed the need for providing phenotypically matched cells for selective antigens especially for Kell and Rh subgroups to reduce risk of alloimmunization and increase the efficiency of blood transfusion.The Mediterranean and Red Sea, which were connected via the Suez Canal during the 19th century after eons of separation, h
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