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The structure for the chemical was tthe variation of influenza A virus resistant to Rimantadine and Amantadine products. The obtained compounds can be used as design frameworks for development of a new drug of direct action against higher level strains of influenza A virus.Results of analysis of phylogenetic, virological, epidemiological, ecological, clinical data of COVID-19 outbreaks in Wuhan, China (PRC) in comparison with SARS-2002 and MERS-2012 outbreaks enable to close out - the etiological broker of COVID-