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Effect of the particular ACY-1 gene in HER2 along with Piste expression throughout rectal carcinoma. As expected, there was a significant reduction in the percentage of proliferative cells that had PI3K inhibited. When compared to TKI 5 treatment, proliferating cells were significantly lower with simultaneous PI3K inhibition. CONCLUSION This study demonstrated that TKI-258 play an anti-proliferative role on SCC-4 cells of OSCC. It could be interesting to block multiples pathways such as FGFRs, P