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etrospective design, the lack of a direct dermoscopic-histological correlation analysis and the small sample size for less common diseases. Obtain European data on SCAD, determine the prevalence of FMD and enable genetic analyses in this population. Data from a national French registry of SCAD cases, were analysed prospectively and retrospectively. Clinical and angiographic data and management strategy were collected. Major adverse cardiovascular events (MACE) were analysed after one-year follow-up. Subjects were screened for fibromuscu