https://www.selleckchem.com/pr....oducts/cct245737.htm
We evaluated the content of active form of TGF-β1 in the intact and post-infarction heart and the effect of this factor on the properties of epicardial cells. During the acute stage after myocardial infarction, the production of TGF-β1 in the heart increased, which closely correlated with activation of epicardial cells (appearance of a pool of Wt1+ epicardial cells entering the epithelial-mesenchymal transition). The role of TGF-β1 as the factor of epicardial activation was confirmed by the results of in vitro experiments addition of

https://www.selleckchem.com/pr....oducts/H-89-dihydroc
The other family members neither had corneal abnormalities nor carried the variant. No keratoplasty is yet planned for the proband. We classify the novel variant in as possibly pathogenic, potentially causing the late-onset, asymmetric variant LCD. Our findings add to the growing number of variants associated with a spectrum of phenotypes of variant LCD. We classify the novel variant in TGFBI as possibly pathogenic, potentially causing the late-onset, asymmetric variant LCD. Our findings add to the growing number of TGFBI v