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Missed, migrated disc fragments can be implicated as a cause of low back pain, radiculopathy or cauda equina syndrome, especially in the absence of visible disc herniation. A high index of suspicion needs to be maintained in those cases with unexplained and persistent symptoms and/or no obvious disc herniation on MR images.We aimed to investigate the effect of aquatic exercise on immune response in pre-frailty elderly women. Forty pre-frailty elderly women were recruited from the Community Center. The 12-week supervised aquatic exercise

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