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The detection price of neovascularization on Angio 6mm×6mm centered on fovea was approximately half of this on Montage 15mm×9mm(P0.05). For microaneurysms, Angio 6mm×6mm had better overall performance than Montage 15mm×9mm (P less then 0.05). CONCLUSIONS Wide field SS-OCTA images had been useful in finding DR lesions. The Angio 12mm × 12mm centered on fovea and optic disc could be an optimal stability between rate and effectiveness for DR assessment in medical practice. Toll like receptor 7 (TLR7)