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Third, the distribution ranking (DR) loss is introduced as the classification loss function to solve the problem of imbalanced data between positive and negative samples. The proposed MSANet is comprehensively compared with other pulmonary nodule detection networks on the LUNA16 dataset, and a CPM score of 0.920 is obtained. The results show that the sensitivity for detecting pulmonary nodules is improved and that the average number of false-positives is effectively reduced. The proposed method has advantages in pulmonary nodule detectio