https://www.selleckchem.com/pr....oducts/Rapamycin.htm
4)/3.4(11.3)/1.3(1.5) N; 5,000 cycles 1.8(0.8)/2.1(1.7)/1.0(1.3) N; 10,000 cycles 1.9(1.6)/2.4(2.5)/1.0(1.4) N, respectively. In contrast to groups A, B, and C, group D did not gain RF when RF values were compared after 5,000 and 10,000 cycles. The loss of RF between baseline (7.0 N) and after 10,000 cycles (5.4 N) was significant only for group D (P = 0.007), but not for groups A, B, and C. Both CAD/CAM-milled and conventionally cast SCs from a high noble metal alloy can provide sufficient RF after 10,000 cycles of artificial aging
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