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Quick telomere lengths, increased CD57 expression, and an expansion of CD8 effector memory T cells re-expressing CD45RA (TEMRA) were additionally found in both patients. Conclusion Unique immunologic abnormalities, CD8 T-cell senescence, and shortened telomere collectively as a hallmark occur in young DC patients before progression to severe disease.Aims The AMBER trial demonstrated that concomitant usage of patiromer allowed the greater persistent utilization of spironolacto