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Results Unexpectedly, the mean preferred directions for the left eye were normal in the monkeys with A-pattern exotropia. For the right eye, there was a clear upward deviation for the right NPH and a downward deviation for the left NPH. In addition, the R2 values were significantly lower for model fits for neurons recorded from the exotropic monkeys. Conclusions We suggest that vertical inconcomitance results from inappropriate vertical-to-horizontal cross-talk that affects the two eyes differently.Purpose To investigate segmented macul