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In clinically node positive patients, a negative 18F-FDG PET/CT was useful in ruling out lymph node metastases (sensitivity 92-100%). This study was limited by its mixed population and focus on pelvic nodal metastases only. CONCLUSIONS 18F-FDG PET/CT appears to be most useful for better characterization of enlarged nodes identified by CT. Routine preoperative 18F-FDG PET/CT has limited utility in clinically node-negative patients.Purpose This study aims to evaluate the accuracy of point-based registration (PBR) when u