https://www.selleckchem.com/pr....oducts/ch6953755.htm
The study randomized 18 patients (mean age 61years); 6 received vehicle (3/6 [50%] female) and 12 patients received OC-01 VNS (11/12 [92%] female). OC-01 VNS treatment decreased mean goblet cell area (pre-treatment, 106.4µm ; post-treatment, 67.6µm ; p = 0.02) and perimeter (pre-treatment, 38.9µm; post-treatment, 31.2µm; p = 0.03) but not vehicle did not (p = 0.25). There were no significant changes in mean meibomian gland area with either treatment (p ≥ 0.05). All TEAEs were non-ocular, non-serious, and mild. This study demonstrated
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