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https://www.selleckchem.com/pr....oducts/z-lehd-fmk-s7
The sensitivity analysis showed postoperative MAP in the acetaminophen group was 1.33 (95% CI, 0.76-1.9 mm Hg lower than in the placebo group (P .001). The median of MAP AUB was 33 [Q1 = 3.3, Q3 = 109] mm Hg × minutes for the treatment and 23 [1.6, 79] mm Hg × minutes for the placebo. Acetaminophen was found to increase the AUB with an estimated median difference of 15 (95% CI, 5-25) mm Hg × minutes (P = .003). Intravenous acetaminophen decreases MAP after its administration. However, this decrease does not appear to be