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No difference was found even when the two SNPs were evaluated in combination. However, this combination was present, as expected, only in a low proportion (3.8%) of the men studied. The SNPs 2039 A/G and -29 G/A in combination did not seem to have any effect on male reproductive function in a cohort of Sicilian men. The effect of these SNPs has only been studied in granulosa cells so far. Further studies on their role in Sertoli cells are needed. The SNPs FSHR 2039 A/G and FSHR -29 G/A in combination did not seem to have any effect on ma
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