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Eighteen days after DEN, a single intraperitoneal dosage of Fe-NTA (5 mg Fe/kg) had been administrated to rats to promote nephrotoxicity. The biochemical variables were examined in serum at time periods while the malondialdehyde (MDA) and tumefaction necrosis factor-alpha (TNF-α) were examined in both serum and renal cells. Kidney from each group was histopathologically examined at time periods. The management of Fe-NTA after DEN dose to albino ra