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These results demonstrate how tension-related mechanosensing may provide an alternative (and potentially complementary) mechanism for cell adaptation.Post-translational modification with one of the isoforms of the small ubiquitin-like modifier (SUMO) affects thousands of proteins in the human proteome. The binding of SUMO to SUMO interacting motifs (SIMs) can translate the SUMOylation event into functional consequences. The E3 ubiquitin ligase RNF4 contains multiple SIMs

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Overall, these findings show that the quality of the diet plays a significant role influencing mammary tumour outcomes.Emissions from biomass burning are very serious in Southeast Asia and South Asia in April. In order to explore the effect of long-range transport of biomass emissions from the Indochina Peninsula in Southwest China during the period of the southeast monsoon season and to find out the main pollution sources in local atmospheric PM2.5, a field campaign was conducted from 6-26 April 2011 in Lijiang, China. Twenty-four-hour