https://www.selleckchem.com/pr....oducts/rottlerin.htm
BACKGROUND Isoindole-1,3(2H)-dione derivatives are known to have cytotoxic effects on many cancer cells. The anticancer activity of these compounds varies depending on the substituents attached to them. Therefore, the effect of substituents is very important when determining the anticancer activities of molecules. We have recently reported an example of the substituent effect. According to that work, the anticancer activity against HeLa, C6, and A549 cancer cell lines of isoindole-1,3(2H)-dione compounds containing tert-butyldiphenyls

https://www.selleckchem.com/products/rki-1447.html
To assess the cumulative risk of progression in glaucomatous eyes in the severe stage of disease. This was a retrospective observational study. Patients that had severe damage in at least one eye, as defined by three criteria including a mean deviation of ≤ - 20dB, were included. Glaucoma progression was defined as a loss of ≥ 2dB in mean deviation confirmed in three consecutive visual field tests, or a persistent loss of two or more lines of vision-not attributable to non-glaucomatous causes-in three consecutive follow-up examinations