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The Best Home Vacuum Cleaner The ideal home vacuum cleaner is a multi-functional tool that is easy to operate and use. The best model must be light, efficient and quiet. has great suction at a reasonable price. It also comes with an anti-hair wrap floorhead that's effective and an odor neutralizing puck. It comes with a bin that is easy to empty. 1. Power A high-powered vacuum cleaner will effectively manage hous

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Idiopathic pulmonary fibrosis (IPF) is a form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, with a poor prognosis. We previously showed the antifibrotic effects of a novel phosphodiesterase 4 (PDE4) inhibitor, AA6216. In this study, we examined the effect of AA6216 on the pulmonary accumulation of segregated-nucleus-containing atypical monocytes (SatMs), which produce tumor necrosis factor (TNF)-α and are involved in murine lung fibrosis. Mice were treated with bleomycin intratracheally at day 0 and