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Median survival time was 13.32 (7.08, 23.28) months in the PD group and 19.68 (9.48, 39.24) months in the HD group, P=.013. After adjustment for confounders the mortality risk amongst PD and HD patients was not significantly different adjusted HR for death in PD vs HD patients was 1.44, P=.35 for 1- year and 1.69, P=.10 for 2-year mortality. Number of hospitalisations was similar in both groups. CHF patient profile was different in PD and HD. Two modalities were equally effective in the treatment of patients with CHF and renal failure

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m6A is one of the most common and abundant modifications of RNA molecules present in eukaryotes. The methyltransferase complex, consisting of methyltransferase-like 3 (METTL3), METTL14, and WTAP, is responsible for the m6A modification of RNA. WTAP was identified as an mRNA splicing regulator. Its role as a regulatory subunit of the m6A methyltransferase complex in embryonic development remains largely unknown. To investigate the role of WTAP in porcine early embryonic development, si-WTAP was microinjected into porcine parthenogenetic z