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52 ± 1.7 mmHg, limits of agreement -2.9 to 3.9 mmHg, r = 0.9, p  less then  0.001). Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. The agreement between static echocardiographic variables of cardiac performance and global heart efficiency lacked robustness. Echocardiographic measurements of cardiac output can be reliably used in calculation of mean systemic filling pressure.An amendment to this paper has been published and can be accessed via a link a